Article
Cytochrome p450 genotyping by multiplexed real-time dna sequencing with pyrosequencing technology.
Assay and drug development technologies - 1 Nov 2002
Eriksson Solveig, Berg Lars M, Wadelius Mia, Alderborn Anders
Abstract excerpt
Individual differences in xenobiotic metabolism influence the therapeutic value of many drugs and are of major concern during the development of new drug candidates. A number of polymorphic cytochrome p450 enzymes account for a significant part of this variation. A better understanding of these g...
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