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Article

PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase.

The Journal of cell biology - 29 May 2000

Suzuki T, Park H, Hollingsworth N M, Sternglanz R, Lennarz W J

Abstract excerpt

It has been proposed that cytoplasmic peptide:N-glycanase (PNGase) may be involved in the proteasome-dependent quality control machinery used to degrade newly synthesized glycoproteins that do not correctly fold in the ER. However, a lack of information about the structure of the enzyme has limited our ability to obtain insight into its precise biological function. A PNGase-defective mutant (png1-1) was...

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Source

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Identifiers

PMID: 10831608
DOI: 10.1083/jcb.149.5.1039
PMCID: PMC2174826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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