Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Studies of yeast Kluyveromyces lactis mutations conferring super-secretion of recombinant proteins.

Yeast (Chichester, England) - 15 Jan 2003

Bartkeviciute Danguole, Sasnauskas Kestutis

Abstract excerpt

We have isolated mutants responsible for a super-secretion phenotype in Kluyveromyces lactis using the gene coding for a Bacillus amyloliquefaciens alpha-amylase as a marker for secretion. These mutations defined two groups, dominant and recessive. The recessive mutant strain, which secreted the heterologous protein in five-fold excess compared to the wild-type strain, was used for the cloning of genes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Gene Dosage
Share to Genes, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kluyveromyces

Share to Molecular Sequence Data

Share to Phenotype

Share to Recombinant Proteins

Share to Saccharomyces cerevisiae

Source

Identifiers

PMID: 12489121
DOI: 10.1002/yea.935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Studies of yeast Kluyveromyces lactis mutations conferring super-secretion of recombinant proteins.PMID 12489121Read ↗

Screening and identification of a gene, PSE-1, that affects protein secretion in Saccharomyces cerevisiae.Semantic proximity Read ↗

Improved production of a heterologous amylase in Saccharomyces cerevisiae by inverse metabolic engineering.Semantic proximity Read ↗

Cloning and functional analysis of the ubiquitin-specific protease gene UBP1 of Saccharomyces cerevisiae.Semantic proximity Read ↗

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast.Semantic proximity Read ↗

Application of the Cre-loxP system for multiple gene disruption in the yeast Kluyveromyces marxianus.Semantic proximity Read ↗

Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretionSemantic proximity Read ↗

RAG1 gene of the yeast Kluyveromyces lactis codes for a sugar transporter.Semantic proximity Read ↗

Characterization of a Saccharomyces cerevisiae mutant with oversecretion phenotype.Semantic proximity Read ↗

Secretion and overproduction of carboxypeptidase Y by a Saccharomyces cerevisiae ssl1 mutant strain.Semantic proximity Read ↗

Targeted deletion of genes encoding extracellular enzymes in Bacillus licheniformis and the impact on the secretion capability.Semantic proximity Read ↗

Isolation and functional analysis of a Kluyveromyces lactis RAP1 homologue.Semantic proximity Read ↗

Kluyveromyces lactis LAC4 promoter variants that lack function in bacteria but retain full function in K. lactis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.