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Article

Mutational analysis of BRAF in gallbladder carcinomas in association with K-ras and p53 mutations and microsatellite instability.

Virchows Archiv : an international journal of pathology - 1 Aug 2004

Saetta Angelica A, Papanastasiou Pollyanthi, Michalopoulos Nikolaos V, Gigelou Fanie, Korkolopoulou Penelope, Bei Thaleia, Patsouris Efstratios

Abstract excerpt

BACKGROUND: Little is known about the genetic changes involved in the pathogenesis of gallbladder cancer. The aim of this study was to examine the presence of mutations in exon 15 of the B-raf gene to investigate its role in gallbladder carcinogenesis. MATERIALS AND METHODS: We examined the mutational status in exon 15 of B-raf gene in 21 gallbladder carcinoma specimens and investigated its association with the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Genes, ras

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Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 15221372
DOI: 10.1007/s00428-004-1046-9

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutational analysis of BRAF in gallbladder carcinomas in association with K-ras and p53 mutations and microsatellite instability.PMID 15221372Read ↗

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