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Article

HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65.

Diabetes - 1 Jul 2004

Tree Timothy I M, Duinkerken Gaby, Willemen Sabine, de Vries René R P, Roep Bart O

Abstract excerpt

HLA-DQ is strongly associated with genetic predisposition to type 1 diabetes. It is assumed that HLA-DQ molecules exert their effects on the disease via the presentation of peptides from islet autoantigens to CD4(+) T-cells, but little information regarding HLA-DQ-restricted, islet antigen-specific, autoreactive T-cells is available. To investigate the role of HLA-DQ in the immune response to islet autoantigens,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15220192
DOI: 10.2337/diabetes.53.7.1692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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