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Article

T cell response pattern to glutamic acid decarboxylase 65 (GAD65) peptides of newly diagnosed type 1 diabetic patients sharing susceptible HLA haplotypes.

Clinical and experimental immunology - 1 Jul 1999

Rharbaoui F, Mayer A, Granier C, Bouanani M, Thivolet C, Pau B, Orgiazzi J, Madec A M

Abstract excerpt

Autoantibodies and autoreactive T lymphocytes directed against several pancreatic beta cell proteins such as GAD65 have been identified in the circulation before and at the onset of clinical type 1 (insulin-dependent) diabetes. Using GAD65 synthetic peptides, we studied the proliferative response of peripheral blood mononuclear cells (PBMC) either from recently diagnosed type 1 diabetic patients, of whom the...

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Identifiers

PMID: 10403912
DOI: 10.1046/j.1365-2249.1999.00945.x
PMCID: PMC1905465

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Source receipt: pubmed, retrieved 7 Sept 2026.

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T cell response pattern to glutamic acid decarboxylase 65 (GAD65) peptides of newly diagnosed type 1 diabetic patients sharing susceptible HLA haplotypes.PMID 10403912Read ↗

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