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CD4⁺ T-cell proliferation responses to wheat polypeptide stimulation in children at different stages of type 1 diabetes autoimmunity.

Pediatric diabetes - 1 May 2015

Hamari Susanna, Kirveskoski Tiina, Glumoff Virpi, Kulmala Petri, Simell Olli, Knip Mikael, Ilonen Jorma, Veijola Riitta

Abstract excerpt

AIMS: Our aim was to study whether immune responses to wheat-based proteins are related to the development of type 1 diabetes. METHODS: We analysed proliferative T-cell responses after in vitro gliadin, gluten, whole wheat, and tetanus toxoid stimulation with a carboxyfluorescein succinimidyl ester (CFSE) based T-cell proliferation assay in children at various phases of type 1 diabetes autoimmunity and in healthy...

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PMID: 25643742
DOI: 10.1111/pedi.12256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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