Article
Antibodies to glutamic acid decarboxylase and insulin-dependent diabetes in patients with autoimmune polyendocrine syndrome type I.
The Journal of clinical endocrinology and metabolism - 1 Apr 1996
Tuomi T, Björses P, Falorni A, Partanen J, Perheentupa J, Lernmark A, Miettinen A
Abstract excerpt
To evaluate the association of autoimmunity to glutamic acid decarboxylase (GAD) with insulin-dependent diabetes mellitus (IDDM) and IDDM-associated human leukocyte antigen (HLA) types, we studied a unique group of 47 patients with autoimmune polyendocrine syndrome type 1, a recessive disease not...
Topics
- Adolescent
- Adult
- Autoantibodies
- C-Peptide
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Female
- Follow-Up Studies
- Genes, MHC Class II
- Genotype
- Glutamate Decarboxylase
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains