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Article

[Colorectal oncogenesis].

Bulletin du cancer - 1 Nov 2010

Laurent-Puig P, Agostini J, Maley K

Abstract excerpt

Recent progress in the field of molecular biology has allowed us to identify at least two different molecular mechanisms implicated in colorectal carcinogenesis (CRC): chromosomal instability (CIN) and genetic instability. Even though the two molecular mechanisms differ, their signalling pathways, implicated in malignant transformation of colonic epithelial cells, appear to be similar. The most frequent group of...

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Source

Identifiers

PMID: 21115420
DOI: 10.1684/bdc.2010.1216

Genes

APC
BAX
BRAF
SMAD2
SMAD4
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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