Article
Polymorphism in genes involved in adrenergic signaling associated with Alzheimer's.
Neurobiology of aging - 1 Aug 2004
Bullido María Jesús, Ramos María Carmen, Ruiz-Gómez Ana, Tutor Antonio S, Sastre Isabel, Frank Anna, Coria Francisco, Gil Pedro, Mayor Federico, Valdivieso Fernando
Abstract excerpt
To investigate the potential involvement of adrenergic signaling in Alzheimer's disease (AD) pathogenesis, we performed genetic and functional studies of genes initiating the cascade. We chose two functional single-nucleotide polymorphisms (SNPs) in the beta1-adrenergic receptor (ADRB1) and the G...
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