Article
Polymorphisms at the beta2-adrenergic receptor gene influence Alzheimer's disease susceptibility.
Brain research - 19 May 2008
Yu Jin-Tai, Tan Lan, Ou Jiang-Rong, Zhu Jun-Xia, Liu Kun, Song Jing-Hui, Sun Yan-Ping
Abstract excerpt
Increasing evidence indicates that the beta2-adrenergic receptor (beta2-AR) may play an important role in Alzheimer's disease (AD). We investigated the effect of two polymorphisms in the beta2-AR gene: Gly16Arg and Gln27Glu for the risk of sporadic Late Onset Alzheimer's Disease (LOAD) in 109 patients and 109 healthy controls matched for sex and age in a Han Chinese population. Results revealed that both the...
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