Article
Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation.
Journal of translational medicine - 10 Mar 2008
Pacanowski Michael A, Zineh Issam, Li Haihong, Johnson B Delia, Cooper-DeHoff Rhonda M, Bittner Vera, McNamara Dennis M, Sharaf Barry L, Merz C Noel Bairey, Pepine Carl J, Johnson Julie A
Abstract excerpt
BACKGROUND: Adrenergic gene polymorphisms are associated with cardiovascular and metabolic phenotypes. We investigated the influence of adrenergic gene polymorphisms on cardiovascular risk in women with suspected myocardial ischemia. METHODS: We genotyped 628 women referred for coronary angiography for eight polymorphisms in the alpha1A-, beta1-, beta2- and beta3-adrenergic receptors (ADRA1A, ADRB1, ADRB2, ADRB3,...
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