Article
Orthogonal analysis of C/EBPbeta targets in vivo during liver proliferation.
Proceedings of the National Academy of Sciences of the United States of America - 31 Aug 2004
Friedman Joshua R, Larris Brian, Le Phillip P, Peiris T Harshani, Arsenlis Athanasios, Schug Jonathan, Tobias John W, Kaestner Klaus H, Greenbaum Linda E
Abstract excerpt
CCAAT enhancer-binding protein beta (C/EBPbeta), a basic-leucine zipper transcription factor, is an important effector of signals in physiologic growth and cancer. The identification of direct C/EBPbeta targets in vivo has been limited by functional compensation by other C/EBP family proteins and the low stringency of the consensus sequence. Here we use the combined power of expression profiling and...
Topics
- Animals
- CCAAT-Enhancer-Binding Protein-beta
- Cell Division
- Gene Expression Regulation
- Liver
- Liver Regeneration
- Mice
- Mutation