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Article

Hepatocyte nuclear factor-3β limits cellular diversity in the developing respiratory epithelium and alters lung morphogenesis in vivo

1 Nov 1997

Abstract excerpt

Hepatocyte nuclear factor-3beta (HNF-3beta), a nuclear protein of the winged helix family of transcription factors, is known to play a critical role in the formation of the embryonic node, notochord, and foregut endoderm. HNF-3beta influences the expression of a number of target genes in the respiratory epithelium, activating transcription of thyroid transcription factor-1, surfactant protein-B and clara cell...

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Identifiers

PMID: 9389455
DOI: 10.1002/(sici)1097-0177(199711)210:3<305::aid-aja10>3.0.co;2-9

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