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Article

Association of ERCC2/XPD polymorphisms and interaction with tobacco smoking in lung cancer susceptibility: a systemic review and meta-analysis.

Molecular biology reports - 1 Jan 2012

Feng Zhen, Ni Yang, Dong Wei, Shen Hongchang, Du Jiajun

Abstract excerpt

The association of the two ERCC polymorphisms, Asp312Asn and Lys751Gln, with lung cancer risk remains controversial and inconclusive. To better evaluate the potential role of the two polymorphisms and interaction with tobacco smoking in lung cancer susceptibility presented in diverse populations,...

Read the complete abstract on PubMed

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Share to Genetic Predisposition to Disease
Share to Lung Neoplasms
Share to Mutation, Missense

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Share to Xeroderma Pigmentosum Group D Protein

Source

Identifiers

PMID: 21614524
DOI: 10.1007/s11033-011-0710-9

Genes

ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21614524-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Association of ERCC2/XPD polymorphisms and interaction with tobacco smoking in lung cancer susceptibility: a systemic review and meta-analysis.PMID 21614524Read ↗

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Polymorphisms in the DNA repair genes XRCC1 and ERCC2, smoking, and lung cancer risk.Semantic proximity Read ↗

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A haplotype encompassing the variant allele of DNA repair gene polymorphism ERCC2/XPD Lys751Gln but not the variant allele of Asp312Asn is associated with risk of lung cancer in a northeastern Chinese population.Semantic proximity Read ↗

The association between XPD Asp312Asn polymorphism and lung cancer risk: a meta-analysis including 16,949 subjects.Semantic proximity Read ↗

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