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Article

Role of polymorphic GSTM1 and GSTT1 genotypes on NNK-induced genotoxicity.

Pharmacogenetics - 1 Dec 1999

Salama S A, Abdel-Rahman S Z, Sierra-Torres C H, Hamada F A, Au W W

Abstract excerpt

Polymorphisms in chemical metabolizing genes are known to influence individual susceptibility to environmental cancer. We investigated the role of GSTM1 and GSTT1 polymorphisms in modifying the genotoxicity of a tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) using the sister chromatid exchange (SCE), and the tandem-probe fluorescence in situ hybridization chromosome aberration...

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Source

Identifiers

PMID: 10634136

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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