Article
XRCC1 gene variants and possible links with chromosome aberrations and micronucleus in active and passive smokers.
Environmental toxicology and pharmacology - 1 Sept 2011
Chandirasekar R, Suresh K, Jayakumar R, Venkatesan R, Lakshman Kumar B, Sasikala K
Abstract excerpt
Tobacco addiction is a major risk for diseases such as cancers, heart attack, etc. Tobacco smoke constitutes environmental toxins that are the major preventable leading cause of death worldwide. We investigated the influence of tobacco smoke on cytogenetic parameters (chromosomal aberrations and micronuclei) and the influence of XRCC1 arg399gln polymorphism on the cytogenetic parameters of the exposed subjects....
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