Article
Effect of a short CAG (glutamine) repeat on human androgen receptor function.
The Prostate - 1 Jan 2004
Ding Dacheng, Xu Lihua, Menon Mani, Reddy G Prem Veer, Barrack Evelyn R
Abstract excerpt
BACKGROUND: The human androgen receptor (AR) gene contains an uninterrupted CAG repeat that is polymorphic in length in the general population (range, 11-31 CAG's; median, 21). The CAG repeat encodes a glutamine repeat in the N-terminal transactivation domain of the AR protein. We previously reported that a 17-CAG AR gene was much more common in a cohort of men with prostate cancer (8.5%) than in the general...
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