Constitutional 1p36 deletion in a child with neuroblastoma.

Article

Constitutional 1p36 deletion in a child with neuroblastoma.

American journal of human genetics - 1 Jan 1993

Biegel J A, White P S, Marshall H N, Fujimori M, Zackai E H, Scher C D, Brodeur G M, Emanuel B S

Abstract excerpt

We describe a child with dysmorphic features, as well as developmental and growth delay, who developed neuroblastoma at 5 mo of age. Cytogenetic analysis of blood lymphocytes revealed an interstitial deletion of 1p36.1-->1p36.2, which was apparent only with high-resolution banding. Molecular anal...

Topics

Adult
Cells, Cultured
Chromosome Mapping
Chromosomes, Human, Pair 1
Female
Gene Deletion
Genes, Tumor Suppressor
Genetic Predisposition to Disease
Humans
Infant, Newborn
Karyotyping
Male
Neuroblastoma
Pedigree

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