Article
Mutations in components of the Wnt signaling pathway in gastric cancer.
World journal of gastroenterology - 14 Mar 2008
Pan Kai-Feng, Liu Wan-Guo, Zhang Lian, You Wei-Cheng, Lu You-Yong
Abstract excerpt
AIM: To explore the contribution of AXIN1, AXIN2 and beta-catenin, components of Wnt signaling pathway, to the carcinogenesis of gastric cancer (GC), we examined AXIN1, AXIN2 exon7 and CTNNB1 (encoding beta-catenin) exon3 mutations in 70 GCs. METHODS: The presence of mutations was identified by p...
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