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Article

Frequent β-catenin gene mutations in atypical polypoid adenomyoma of the uterus.

Human pathology - 1 Jan 2014

Takahashi Hiroyuki, Yoshida Tsutomu, Matsumoto Toshihide, Kameda Yoichi, Takano Yasuo, Tazo Yuki, Inoue Hisako, Saegusa Makoto

Abstract excerpt

Atypical polypoid adenomyoma (APA) is an uncommon polypoid lesion of the uterus. To clarify the mechanism of its histogenesis, we examined the functional role of β-catenin, with reference to expression of p21(waf1), cyclin D1, cyclin E, CD10, and α-smooth muscle actin (SMA), as well as cell proliferation, in 7 lesions. In the epithelial components, expression of nuclear β-catenin, p21(waf1), and cyclin D1 was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24182564
DOI: 10.1016/j.humpath.2013.06.020

Genes

CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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