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Article

Wnt/β-catenin signal alteration and its diagnostic utility in basal cell adenoma and histologically similar tumors of the salivary gland.

Pathology, research and practice - 1 Apr 2018

Sato Masanobu, Yamamoto Hidetaka, Hatanaka Yui, Nishijima Toshimitsu, Jiromaru Rina, Yasumatsu Ryuji, Taguchi Kenichi, Masuda Muneyuki, Nakagawa Takashi, Oda Yoshinao

Abstract excerpt

Differential diagnosis among basal cell adenoma (BCA), basal cell adenocarcinoma (BCAC), adenoid cystic carcinoma (ACC) and pleomorphic adenoma (PA) of the salivary gland can be challenging due to their similar histological appearance. Although frequent nuclear β-catenin expression and CTNNB1 mutations have been reported in BCA, further details of the Wnt/β-catenin signal alterations are unclear. The aim of this...

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Source

Identifiers

PMID: 29496310
DOI: 10.1016/j.prp.2017.12.016

Genes

CTNNB1
APC
AXIN1
MYB
MYBL1
AXIN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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