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Article

Immunohistochemical and sequencing analyses of the Wnt signaling components in Japanese anaplastic thyroid cancers.

Thyroid : official journal of the American Thyroid Association - 1 Dec 2004

Kurihara Takeshi, Ikeda Satoshi, Ishizaki Yasuyo, Fujimori Masahiko, Tokumoto Noriaki, Hirata Yuzoh, Ozaki Shinji, Okajima Masazumi, Sugino Keizo, Asahara Toshimasa

Abstract excerpt

We investigated the status of the components and target genes of the Wnt signaling pathway in Japanese anaplastic thyroid cancers (ATCs) in the present study. Nuclear and cytoplasmic positive staining of beta-catenin, which might indicate the existence of alterations in the Wnt signaling pathway, were found in 40.9% and 63.6% of the 22 ATC samples, respectively. The beta-catenin, adenomatous polyposis coli (APC)...

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PMID: 15650354
DOI: 10.1089/thy.2004.14.1020

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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