Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of a novel alteration of the Axin gene in various pediatric neoplasms.

Oncology reports - 1 Jan 2000

Miao Jiangyong, Kusafuka Takeshi, Okada Akira

Abstract excerpt

The Wnt signaling pathway is conserved in various species from worms to mammals, and plays critical roles in development, cellular proliferation and differentiation. As part of Wnt signal transduction, the function of the Axin complex is inhibited, leading to the accumulation of beta-catenin prot...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axin Protein
Share to beta Catenin
Share to Codon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoskeletal Proteins

Share to Introns

Share to Polymorphism, Single-Stranded Conformational

Share to Repressor Proteins

Share to Trans-Activators

Source

Identifiers

PMID: 14534723
DOI: 10.3892/or.10.6.1943

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14534723-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of a novel alteration of the Axin gene in various pediatric neoplasms.PMID 14534723Read ↗

Axin, the main component of the Wnt signaling pathway, is not mutated in kidney tumors in children.Semantic proximity Read ↗

The links between axin and carcinogenesisSemantic proximity Read ↗

AXIN1 mutations but not deletions in cerebellar medulloblastomas.Semantic proximity Read ↗

Mutations in AXIN2 gene as a risk factor for tooth agenesis and cancer: A review.Semantic proximity Read ↗

AXIN1 and AXIN2 variants in gastrointestinal cancers.Semantic proximity Read ↗

Tumor formation by genetic mutations in the components of the Wnt signaling pathway.Semantic proximity Read ↗

Mutation analysis of CTNNB1 (beta-catenin) and AXIN1, the components of Wnt pathway, in cervical carcinomas.Semantic proximity Read ↗

Novelty of Axin 2 and lack of Axin 1 gene mutation in colorectal cancer: a study in Kashmiri population.Semantic proximity Read ↗

Functional analysis of a novel missense mutation in AXIN2 associated with non-syndromic tooth agenesis.Semantic proximity Read ↗

Diversity of axin in signaling pathways and its relation to colorectal cancer.Semantic proximity Read ↗

Case report expanding the germline AXIN2- related phenotype to include olfactory neuroblastoma and gastric adenoma.Semantic proximity Read ↗

Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin SignalingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.