Article
Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium.
Molecular biology of the cell - 1 Aug 2004
Gebbie Leigh, Benghezal Mohammed, Cornillon Sophie, Froquet Romain, Cherix Nathalie, Malbouyres Marilyne, Lefkir Yaya, Grangeasse Christophe, Fache Sébastien, Dalous Jérémie, Brückert Franz, Letourneur François, Cosson Pierre
Abstract excerpt
The amoeba Dictyostelium is a simple genetic system for analyzing substrate adhesion, motility and phagocytosis. A new adhesion-defective mutant named phg2 was isolated in this system, and PHG2 encodes a novel serine/threonine kinase with a ras-binding domain. We compared the phenotype of phg2 null cells to other previously isolated adhesion mutants to evaluate the specific role of each gene product. Phg1, Phg2,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
