Article
SadA, a novel adhesion receptor in Dictyostelium.
The Journal of cell biology - 23 Dec 2002
Fey Petra, Stephens Stephen, Titus Margaret A, Chisholm Rex L
Abstract excerpt
Little is known about cell-substrate adhesion and how motile and adhesive forces work together in moving cells. The ability to rapidly screen a large number of insertional mutants prompted us to perform a genetic screen in Dictyostelium to isolate adhesion-deficient mutants. The resulting substrate adhesion-deficient (sad) mutants grew in plastic dishes without attaching to the substrate. The cells were often...
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