Article
TM9/Phg1 and SadA proteins control surface expression and stability of SibA adhesion molecules in Dictyostelium.
Molecular biology of the cell - 1 Feb 2012
Froquet Romain, le Coadic Marion, Perrin Jackie, Cherix Nathalie, Cornillon Sophie, Cosson Pierre
Abstract excerpt
TM9 proteins form a family of conserved proteins with nine transmembrane domains essential for cellular adhesion in many biological systems, but their exact role in this process remains unknown. In this study, we found that genetic inactivation of the TM9 protein Phg1A dramatically decreases the surface levels of the SibA adhesion molecule in Dictyostelium amoebae. This is due to a decrease in sibA mRNA levels,...
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