Article
Association between COL3A1 collagen gene exon 31 polymorphism and risk of floppy mitral valve/mitral valve prolapse.
International journal of cardiology - 1 Jun 2004
Chou Hsiang-Tai, Hung Jui-Sung, Chen Yng-Tay, Wu Jer-Yuarn, Tsai Fuu-Jen
Abstract excerpt
BACKGROUND: Collagen structure is a key element in mitral valves. Collagen defects were proposed as the primary events causing floppy mitral valves (FMV). The role of collagen genetic variant in floppy mitral valve/mitral valve prolapse (FMV/MVP) has not been well studied. The purpose of this study is to investigate the possible relationship between the collagen gene polymorphisms and risk of FMV/MVP among the...
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