Article
Collagen type 3 alpha 1 polymorphism and risk of pelvic organ prolapse.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics - 1 Oct 2008
Chen Huey-Yi, Chung Ya-Wen, Lin Wei-Yong, Wang Jiunn-Chin, Tsai Fuu-Jen, Tsai Chang-Hai
Abstract excerpt
OBJECTIVE: To investigate whether pelvic organ prolapse (POP) is associated with collagen 3 alpha 1 (COL3A1) polymorphisms and other factors. METHODS: A case-control association study was conducted with 84 women affected with POP and 147 controls. The genotypes of nucleotides COL3A1 rs1800255 and COL3A1 rs1801184 polymorphisms were ascertained by polymerase chain reaction and restriction fragment length...
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