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Article

Association between fibrillin-1 gene exon 15 and 27 polymorphisms and risk of mitral valve prolapse.

The Journal of heart valve disease - 1 Jul 2003

Chou Hsiang-Tai, Shi Yi-Ru, Hsu Yuan, Tsai Fuu-Jen

Abstract excerpt

BACKGROUND AND AIM OF THE STUDY: Fibrillin is one of the structural components of the elastin-associated microfibrils found in the mitral valve. Abnormalities of elastic fiber were found in floppy mitral valves. The role of fibrillin genetic variant in isolated mitral valve prolapse (MVP) has not been studied. Hence, a case-controlled study was performed to investigate the relationship between fibrillin-1 gene...

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Source

Identifiers

PMID: 12918850

Genes

MVP
FBN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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