Article
Matrix Metalloproteinase Polymorphisms in Patients with Floppy Mitral Valve/Mitral Valve Prolapse (FMV/MVP) and FMV/MVP Syndrome.
Cardiology - 1 Jan 2000
Lima Sarah M, Pitsis Antonios A, Kelpis Timotheos G, Shahin Mohamed H, Langaee Taimour Y, Cavallari Larisa H, Theofilogiannakos Efstratios K, Boudoulas Harisios, Boudoulas Konstantinos Dean
Abstract excerpt
BACKGROUND: It has been suggested that collagen abnormalities of the mitral valve are present in patients with floppy mitral valve (FMV)/mitral valve prolapse (MVP). Genetic factors determining collagen synthesis and degradation have not been well defined in these patients. This study was undertaken to determine whether selective polymorphisms of matrix metalloproteinase-2 (MMP2) or transforming growth factor-β...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.