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Article

Lack of association between transforming growth factor-beta1 gene polymorphisms and mitral valve prolapse in Taiwan Chinese.

The Journal of heart valve disease - 1 Jul 2002

Chou Hsiang-Tai, Shi Yi-Ru, Hsu Yuan, Tsai Fuu-Jen

Abstract excerpt

BACKGROUND AND AIMS OF THE STUDY: A role of collagen abnormality in the pathogenesis of mitral valve prolapse (MVP) has been addressed. It is considered that transforming growth factor-beta1 (TGF-beta1) may be responsible for the increased deposition of extracellular matrix in hypertensive blood vessels, and increased myocardial collagen expression and myocardial fibrosis in human aortic valve disease. However,...

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Source

Identifiers

PMID: 12150293

Genes

MVP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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