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Article

<i>Tbx5</i>specifies the left/right ventricles and ventricular septum position during cardiogenesis

28 Oct 2003

Abstract excerpt

Extensive misexpression studies were carried out to explore the roles played by Tbx5, the expression of which is excluded from the right ventricle (RV) during cardiogenesis. When Tbx5 was misexpressed ubiquitously, ventricular septum was not formed, resulting in a single ventricle. In such heart, left ventricle (LV)-specific ANF gene was induced. In search of the putative RV factor(s), we have found that chick...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 14573514
DOI: 10.1242/dev.00797

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