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Article

In vivo function of desmosomes.

The Journal of dermatology - 1 Mar 2004

Cheng Xing, Koch Peter J

Abstract excerpt

Desmosomes are morphologically and biochemically defined cell-cell junctions that are required for maintaining the mechanical integrity of skin and the heart in adult mammals. Furthermore, since mice with null mutations in desmosomal plaque proteins (plakoglobin and desmoplakin) die in utero, it is also evident that desmosomes are indispensable for normal embryonic development. This review focuses on the role of...

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Identifiers

PMID: 15187337
DOI: 10.1111/j.1346-8138.2004.tb00654.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Desmosomes and disease: an update.Semantic proximity Read ↗

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Molecular abnormalities of the desmosomal protein desmoplakin in human disease.Semantic proximity Read ↗

Desmosomes: differentiation, development, dynamics and diseaseSemantic proximity Read ↗

Mutations in genes encoding desmosomal proteins: spectrum of cutaneous and extracutaneous abnormalities.Semantic proximity Read ↗

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