Article
Desmosomal genodermatoses.
The British journal of dermatology - 1 Jan 2012
Petrof G, Mellerio J E, McGrath J A
Abstract excerpt
Desmosomes are intercellular junctions that contribute to cell-cell adhesion, signalling, development and differentiation in various tissues, including the skin. Composed of a network of transmembranous and intracellular plaque proteins, pathogenic autosomal dominant or recessive mutations have been reported in 10 different desmosomal genes, resulting in a spectrum of phenotypes variably affecting skin, hair and...
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