Article
Inherited desmosomal disorders.
Cell and tissue research - 1 Jun 2015
Samuelov Liat, Sprecher Eli
Abstract excerpt
Desmosomes serve as intercellular junctions in various tissues including the skin and the heart where they play a crucial role in cell-cell adhesion, signalling and differentiation. The desmosomes connect the cell surface to the keratin cytoskeleton and are composed of a transmembranal part consisting mainly of desmosomal cadherins, armadillo proteins and desmoplakin, which form the intracytoplasmic desmosomal...
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