Article
Proteomic analysis reveals a role for protein kinase C-alpha in phagosome maturation.
Biochemical and biophysical research communications - 2 Jul 2004
Ng Yan Hing John Derek, Desjardins Michel, Descoteaux Albert
Abstract excerpt
Acquisition of microbicidal properties by phagosomes requires the action of molecules which regulate the interactions between phagosomes and endocytic organelles. Members of the protein kinase C (PKC) superfamily of serine/threonine kinases are recruited to phagosomes with various kinetics during phagolysosome biogenesis. To study the role of PKC-alpha in this process, we compared the composition of latex...
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