Article

Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular collagen

2022-05-19

Abstract excerpt

<h4>ABSTRACT</h4> Resident tissue macrophages (RTMs) are organ-specialized phagocytes responsible for the maintenance and protection of tissue homeostasis. It is well established that tissue diversity is reflected by the heterogeneity of RTMs origin and phenotype. However, much less is known about tissue-specific phagocytic and proteolytic macrophage functions. Here, using quantitative proteomics approach, we ide...

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Literature Corpus work: 1aca9b5f-9d83-5231-bc6e-f5bb17cbb501
DOI: 10.1101/2022.05.16.492085

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