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Article

Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy.

The EMBO journal - 6 Sept 2006

Kaushik Susmita, Massey Ashish C, Cuervo Ana Maria

Abstract excerpt

Chaperone-mediated autophagy (CMA) is a selective mechanism for the degradation of soluble cytosolic proteins in lysosomes. The limiting step of this type of autophagy is the binding of substrates to the lysosome-associated membrane protein type 2A (LAMP-2A). In this work, we identify a dynamic s...

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Identifiers

PMID: 16917501
DOI: 10.1038/sj.emboj.7601283
PMCID: PMC1560360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16917501-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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