Article
No evidence of association between Catechol-O-Methyltransferase (COMT) Val158Met genotype and performance on neuropsychological tasks in children with ADHD: a case-control study.
BMC psychiatry - 7 Jun 2004
Mills Sophie, Langley Kate, Van den Bree Marianne, Street Eddy, Turic Darko, Owen Michael J, O'Donovan Michael C, Thapar Anita
Abstract excerpt
BACKGROUND: Several studies have suggested an association between the functional Val158Met polymorphism in the Catechol-O-Methyltransferase (COMT) gene and neurocognitive performance. Two studies showed that subjects with the low activity Met allele performed better on the Wisconsin Card Sorting Test (WCST) and another study found an effect on processing speed and attention. METHODS: We set out to examine the...
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