Article
Catechol-o-methyltransferase gene and executive function in children with ADHD.
Journal of attention disorders - 1 Apr 2014
Choudhry Zia, Sengupta Sarojini, Thakur Geeta, Page Veronique, Schmitz Norbert, Grizenko Natalie, Joober Ridha
Abstract excerpt
OBJECTIVE: To examine the association between functional haplotypes in the catechol-o-methyltransferase (COMT) gene and ADHD diagnosis, and executive function (EF) in children with ADHD. METHOD: COMT single nucleotide polymorphism (SNPs; rs6269, rs4633, rs4818, and rs4680) were genotyped in 445 ADHD children. EF was assessed using Wisconsin Card Sorting Test (WCST), Tower of London, and self-ordered pointing...
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