Article
Complex association analysis of graves disease using a set of polymorphic markers.
Molecular genetics and metabolism - 1 Jul 2000
Chistyakov D A, Savost'anov K V, Turakulov R I, Petunina N A, Trukhina L V, Kudinova A V, Balabolkin M I, Nosikov V V
Abstract excerpt
Graves disease is complex autoimmune thyrotoxicosis. A number of genes may contribute to the development of the disorder. Some of them may be genes that encode cytotoxic T-lymphocyte-associated serine esterase-4 (CTLA4), subunit 2 of large multifunctional protease (LMP2), thyroid-stimulating hormone receptor (TSHR), and interleukin 1 receptor antagonist (IL1RN). We studied polymorphism of Ala17Thr CTLA4, H60R...
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