Article
Cre-mediated recombination in cell lineages that express the progesterone receptor.
Genesis (New York, N.Y. : 2000) - 1 Feb 2005
Soyal Selma M, Mukherjee Atish, Lee Kevin Y-S, Li Jie, Li Huaiguang, DeMayo Francesco J, Lydon John P
Abstract excerpt
Using gene-targeting methods, a progesterone receptor Cre knockin (PR-Cre) mouse was generated in which Cre recombinase was inserted into exon 1 of the PR gene. The insertion positions the Cre gene downstream (and under the specific control) of the endogenous PR promoter. As for heterozygotes for the progesterone receptor knockout (PRKO) mutation, mice heterozygous for the Cre knockin insertion are phenotypically...
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