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Research Resource: Progesterone Receptor Targetome Underlying Mammary Gland Branching Morphogenesis

27 Aug 2013

Abstract excerpt

Progesterone (P4)-activated progesterone receptors (PRs) play an essential role in driving pregnancy-associated mammary ductal side-branching morphogenesis and alveologenesis. However, the global cistromic and transcriptome responses that are required to elicit P4-dependent branching morphogenesis have not been elucidated. By combining chromatin immunoprecipitation followed by deep sequencing to identify...

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PMID: 23979845
DOI: 10.1210/me.2013-1144

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