Article
A reappraisal of progesterone action in the mammary gland.
Journal of mammary gland biology and neoplasia - 1 Jul 2000
Lydon J P, Sivaraman L, Conneely O M
Abstract excerpt
The ovarian hormones estrogen and progesterone and their respective receptors are essential for maintenance of postnatal developmental plasticity of the mammary gland and play a key role in mammary tumorigenesis. Mouse models in which expression of the progesterone receptors was genetically ablated have recently become available. Studies of these models have demonstrated that progesterone is specifically required...
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