Article
Endocrine defects in mice carrying a null mutation for the progesterone receptor gene.
Endocrinology - 1 Oct 1997
Chappell P E, Lydon J P, Conneely O M, O'Malley B W, Levine J E
Abstract excerpt
Mice carrying a null mutation of the progesterone receptor gene exhibit several reproductive abnormalities, including anovulation, attenuated lordotic behavior, uterine hyperplasia, and lack of mammary gland development. The hormonal correlates of these abnormalities are unknown, however, and were the focus of these studies. Serum samples from female wild-type (WT) and progesterone receptor knockout (PRKO) mice...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.