Article
Pneumocystis jiroveci isolates with dihydropteroate synthase mutations in patients with chronic bronchitis.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Jul 2004
Calderón E, de la Horra C, Medrano F J, López-Suárez A, Montes-Cano M A, Respaldiza N, Elvira-González J, Martín-Juan J, Bascuñana A, Varela J M
Abstract excerpt
Since mutations in the dihydropteroate synthase (DHPS) gene possibly associated with sulfonamide resistance have been reported in patients with Pneumocystis jiroveci (previously carinii) pneumonia, and since P. jiroveci colonization has been recently demonstrated in patients with chronic pulmonary diseases, the present study aimed to investigate the possible occurrence of P. jiroveci DHPS mutations in patients...
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