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Article

Study of dihydropteroate synthase (DHPS) gene mutations among isolates of Pneumocystis jiroveci.

The Indian journal of medical research - 1 Dec 2008

Tyagi A K, Mirdha B R, Guleria Randeep, Mohan Anant, Luthra Kalpana, Singh U B

Abstract excerpt

BACKGROUND & OBJECTIVES: Pneumocystis jiroveci (also known as P. carinii) causes fatal pneumonia in patients with AIDS and other immunocompromised patients. Co-trimoxazole (trimethoprim + sulphamethoxazole, TMP-SMZ) is the drug of choice for treatment and prophylaxis. Widespread use of sulpha medication has raised the possible selection of resistant P. jiroveci strains worldwide. Non-synonymous polymorphisms...

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PMID: 19246797

Genes

DHPS

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