Article
Dihydropteroate synthase gene mutations in Pneumocystis jiroveci strains isolated from immunocompromised patients.
Pathologie-biologie - 1 Aug 2011
Jarboui M A, Sellami A, Sellami H, Cheikhrouhou F, Makni F, Ayadi A
Abstract excerpt
The emergence of Pneumocystis jiroveci drug resistance has been suggested recently by the mutations in the gene encoding dihydropteroate synthase (DHPS). The aim of the present study was to determine the prevalence of DHPS mutations in P. jiroveci strains isolates from bronchoalveolar lavages (BAL) and sputum samples of 21 immunocompromised patients. We used the touchdown-PCR for amplification of DHPS gene and...
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