Article
Detection of Pneumocystis jirovecii dihydropteroate synthase polymorphisms in patients with Pneumocystis pneumonia.
Scandinavian journal of infectious diseases - 1 Jan 2005
Costa M C, Gaspar J, Mansinho K, Esteves F, Antunes F, Matos O
Abstract excerpt
In the present study, in order to improve the detection of Pneumocystis jirovecii dihydropteroate synthase (DHPS) mutations in pulmonary specimens of HIV-infected patients with P. jirovecii pneumonia, we evaluated a microfiltration procedure for the removal of human cell contamination and a nested-PCR method, for amplification in specimens with low parasite load. In the studied population, PCR amplification of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
